Activity Info

Limb-girdle muscular dystrophy (LGMD) can be difficult to recognize, with heterogeneous presentations and overlap with other neuromuscular disorders contributing to diagnostic delays. With more than 30 genetically distinct disorders, identifying the specific LGMD subtype is increasingly important for prognosis, management, and readiness for emerging targeted therapies. Explore evidence-based strategies for recognizing LGMD earlier and navigating diagnostic pathways. Examine how genetic testing can support accurate subtype classification and inform management decisions, including challenges surrounding test selection and interpretation. Then, assess emerging evidence for novel approaches targeting specific LGMD subtypes and consider what an evolving therapeutic landscape could mean for your patients.